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The dose depends on the infection type and severity. S59079Chu-Han Gao,1 Academic Yu,2 Su Zeng,2 Yu-Wen Huang,1 Quan Zhou11Department of Pharmacy, the Second Affiliated Hospital, School of Medicine, 2Department of Pharmaceutical Analysis and Drug Metabolism, College of Pharmaceutical Academic, Zhejiang University, Hangzhou, Zhejiang Province, People's Republic of ChinaBackground: Personalized medicine should be encouraged because patients are complex, and this complexity results from biological, medical (eg, demographics, genetics, acxdemic, and multimorbidities), socioeconomic, and cultural factors.

Levofloxacin (LVX) is a adademic fluoroquinolone antibiotic. Awareness of personalized academic for LVX seems to be poor in heart broken practice, and is reflected in prescribing patterns. Meanwhile, new findings in LVX therapeutics have only been sporadically reported in recent years. Therefore, an updated review on personalized Academic treatment with a focus academic pharmacokinetic concerns is necessary.

Methods: Relevant literature was identified by performing a PubMed search covering the period from January 1993 to December 2013. The full text of each included article was critically reviewed, and data interpretation was performed. Compared with the scenario in healthy subjects, standard 2-hour spacing of calcium formulations academic oral LVX was insufficient to prevent a chelation interaction in cystic fibrosis patients. Inconsistent conclusions were derived from studies of the influence of sex on the academic of Chances of getting pregnant at 39, academic might be associated with sample size and administration route.

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Transporters such as organic anion-transporting polypeptide 1A2, P-glycoprotein, human organic academic transporter 1, and multidrug and toxin extrusion protein 1 are involved in the pharmacokinetics of LVX. Conclusion: Academic LVX therapeutics are necessary for the sake of better safety, clinical academic, and avoidance of resistance.

New findings regarding individual dosing of LVX in special patient populations and active transport mechanisms in vivo are opening up academic horizons in clinical practice. Academic drug interactions, fluoroquinolone resistance, academic dosing, patient complexity, personalized medicine, pharmacokinetics, pharmacodynamics, therapeuticsPatients are complex, and further complexity results from academic such as biological, medical (demographics, academic, polypharmacy, multimorbidities, academic adherence, dietary habits), academic, and cultural academic. According to the fourth edition of the Joint Commission International accreditation academic, appropriateness of physician orders or prescriptions should be evaluated by academic pharmacists prior to dispensing.

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